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2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitorsEnalapril — A study was conducted to assess the interaction of enalapril (10 to 20 mg daily) and tadalafil 10 mg. Following dosing, the mean reduction in supine systolic/diastolic blood pressure due to tadalafil 10 mg in subjects taking enalapril was 4/1 mm Hg, compared to placebo.
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Switching from one of the oral medicines to another may be tried before proceeding to a more invasive or costlier treatment. However, there are few studies that show any one of the drugs being significantly more effective than another. heart disease, heart rhythm problems;
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